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Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection (BATCH): protocol for a randomised controlled trial.
Waldron CA, Thomas-Jones E, Bernatoniene J, Brookes-Howell L, Faust SN, Harris D, Hinds L, Hood K, Huang C, Mateus C, Pallmann P, Patel S, Paulus S, Peak M, Powell C, Preston J, Carrol ED. Waldron CA, et al. BMJ Open. 2022 Jan 25;12(1):e047490. doi: 10.1136/bmjopen-2020-047490. BMJ Open. 2022. PMID: 35078830 Free PMC article.
A review conducted for National Institute for Health and Care Excellence recommends further research on PCT testing to guide antibiotic use in children. METHODS AND ANALYSIS: Biomarker-guided duration of Antibiotic Treatment in …
A review conducted for National Institute for Health and Care Excellence recommends further research on PCT testing to guide antibiotic
PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO): protocol for a multicentre, open-label, randomised controlled trial.
Euden J, Thomas-Jones E, Aston S, Brookes-Howell L, Carman J, Carrol E, Gilbert S, Howard P, Hood K, Inada-Kim M, Llewelyn M, McGill F, Milosevic S, Niessen LW, Nsutebu E, Pallmann P, Schmidt P, Taylor-Robinson D, Welters I, Todd S, French N; PRONTO team.. Euden J, et al. BMJ Open. 2022 Jun 13;12(6):e063424. doi: 10.1136/bmjopen-2022-063424. BMJ Open. 2022. PMID: 35697438 Free PMC article.
Despite this, there is a tendency to overemphasise the score in isolation in patients with suspected infection, leading to the overprescription of antibiotics and potentially treatment-related complications and rising antimicrobial resistance. The biom …
Despite this, there is a tendency to overemphasise the score in isolation in patients with suspected infection, leading to the …